USP10: Friend and Foe

نویسندگان

  • Aart G. Jochemsen
  • Yosef Shiloh
چکیده

The tumor suppressor protein p53, a crucial player in the DNA damage response, is regulated in many ways, most notably through ubiquitination. In this issue, Yuan et al. (2010) identify the deubiquitinating protease USP10 as a new regulator of p53 in the DNA damage response and tumor development.

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عنوان ژورنال:
  • Cell

دوره 140  شماره 

صفحات  -

تاریخ انتشار 2010